Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
Identifieur interne : 000019 ( Main/Curation ); précédent : 000018; suivant : 000020Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
Auteurs : Vesper Fe Marie L. Ramos ; Ajay S. Pillai ; Codrin Lungu ; Jill Ostrem ; Philip Starr ; Mark HallettSource :
- Annals of Clinical and Translational Neurology [ 2328-9503 ] ; 2015.
Abstract
Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus pallidus internus were retrospectively compared with those of five patients with known DYT1 dystonia using spontaneous discharge parameters of rate and bursting, as well as movement-related discharges. Our data suggest that simple intraoperative neurophysiology measures in single subjects do not differentiate psychogenic dystonia from DYT1 dystonia.
Url:
DOI: 10.1002/acn3.206
PubMed: 26125045
PubMed Central: 4479530
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<front><div type="abstract" xml:lang="en"><p>Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus pallidus internus were retrospectively compared with those of five patients with known DYT1 dystonia using spontaneous discharge parameters of rate and bursting, as well as movement-related discharges. Our data suggest that simple intraoperative neurophysiology measures in single subjects do not differentiate psychogenic dystonia from DYT1 dystonia.</p>
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